Detailed Record



Two Distinct Biotypes in Major Depression Unveiled


Abstract Major depressive disorder (MDD) is a globally prevalent mental health condition that exhibits diverse clinical features and a complex genetic makeup. Despite attempts to classify its heterogeneous presentation based on symptoms, these approaches, which are rooted in the diverse biological mechanisms of comparable symptoms, have not yielded treatment options grounded in empirical evidence (1). Addressing this challenge requires a direct stratification of biological heterogeneity by objectively identifying biotypes.
Authors Rammohan Shukla University of WyomingORCID
Journal Info Elsevier BV | Biological Psychiatry , vol: 95 , iss: 5 , pages: 382 - 384
Publication Date 3/1/2024
ISSN 0006-3223
TypeKeyword Image article
Open Access closed Closed Access
DOI https://doi.org/10.1016/j.biopsych.2023.11.026
KeywordsKeyword Image Depression Symptoms (Score: 0.568692) , Depression (Score: 0.536911) , Psychopathology (Score: 0.50846)