Detailed Record



Microfluidic platforms in diagnostic of ovarian cancer


Abstract The most important reason for death from ovarian cancer is the late diagnosis of this disease. The standard treatment of ovarian cancer includes surgery and chemotherapy based on platinum, which is associated with side effects for the body. Due to the nonspecific nature of clinical symptoms, developing a platform for early detection of this disease is needed. In recent decades, the advancements of microfluidic devices and systems have provided several advantages for diagnosing ovarian cancer. Designing and manufacturing new platforms using specialized technologies can be a big step toward improving the prevention, diagnosis, and treatment of this group of diseases. Organ-on-a-chip microfluidic devices are increasingly used as a promising platform in cancer research, with a focus on specific biological aspects of the disease. This review focusing on ovarian cancer and microfluidic application technologies in its diagnosis. Additionally, it discusses microfluidic platforms and their potential future perspectives in advancing ovarian cancer diagnosis.
Authors Farnaz Dabbagh Moghaddam , Delara Dadgar , Yasaman Esmaeili , Shahrzad Babolmorad , Ehsan Ilkhani ORCID , Mahdi Rafiee University of WyomingORCID , Xiangdong Wang ORCID , Pooyan Makvandi ORCID
Journal Info Elsevier BV | Environmental Research , vol: 237 , pages: 117084 - 117084
Publication Date 11/1/2023
ISSN 0013-9351
TypeKeyword Image article
Open Access hybrid Hybrid Access
DOI https://doi.org/10.1016/j.envres.2023.117084
KeywordsKeyword Image Microfluidic Devices (Score: 0.533304)