Abstract |
Lung cancer has been one of the leading causes of death over the past century. Unfortunately, the reliance on conventional methods to diagnose the phenotypic properties of tumors hinders early-stage cancer diagnosis. However, recent advancements in identifying disease-specific nucleotide biomarkers, particularly microRNAs, have brought us closer to early-stage detection. The roles of miR-155, miR-197, and miR-182 have been established in stage I lung cancer. Recent progress in synthesizing nanomaterials with higher conductivity has enhanced the diagnostic sensitivity of electrochemical biosensors, which can detect low concentrations of targeted biomarkers. Therefore, this review article focuses on exploring electrochemical biosensors based on microRNA in lung cancer. |
Authors |
Donya Shaterabadi , Maryam Zamani Sani , Fereshteh Rahdan , Mohammad Taghi Taghizadeh , Mahdi Rafiee  , Nafiseh Dorosti , Aria Dianatinasab , Mortaza TaheriāAnganeh , Peyman Asadi , Seyyed Hossein Khatami , Ahmad Movahedpour
|
Journal Info |
Elsevier BV | Clinica Chimica Acta , vol: 552
, pages: 117676 - 117676
|
Publication Date |
1/1/2024 |
ISSN |
0009-8981 |
Type |
article |
Open Access |
closed
|
DOI |
https://doi.org/10.1016/j.cca.2023.117676 |
Keywords |
Biosensors (Score: 0.583264) , cancer diagnostics (Score: 0.558281) , Biomarkers (Score: 0.522461) , MicroRNAs (Score: 0.508239)
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