Detailed Record



MicroRNA biosensors in lung cancer


Abstract Lung cancer has been one of the leading causes of death over the past century. Unfortunately, the reliance on conventional methods to diagnose the phenotypic properties of tumors hinders early-stage cancer diagnosis. However, recent advancements in identifying disease-specific nucleotide biomarkers, particularly microRNAs, have brought us closer to early-stage detection. The roles of miR-155, miR-197, and miR-182 have been established in stage I lung cancer. Recent progress in synthesizing nanomaterials with higher conductivity has enhanced the diagnostic sensitivity of electrochemical biosensors, which can detect low concentrations of targeted biomarkers. Therefore, this review article focuses on exploring electrochemical biosensors based on microRNA in lung cancer.
Authors Donya Shaterabadi , Maryam Zamani Sani , Fereshteh Rahdan , Mohammad Taghi Taghizadeh ORCID , Mahdi Rafiee University of WyomingORCID , Nafiseh Dorosti , Aria Dianatinasab , Mortaza Taheriā€Anganeh ORCID , Peyman Asadi , Seyyed Hossein Khatami ORCID , Ahmad Movahedpour ORCID
Journal Info Elsevier BV | Clinica Chimica Acta , vol: 552 , pages: 117676 - 117676
Publication Date 1/1/2024
ISSN 0009-8981
TypeKeyword Image article
Open Access closed Closed Access
DOI https://doi.org/10.1016/j.cca.2023.117676
KeywordsKeyword Image Biosensors (Score: 0.583264) , cancer diagnostics (Score: 0.558281) , Biomarkers (Score: 0.522461) , MicroRNAs (Score: 0.508239)